Wooly Mammoth Genes Inserted into Elephant Cells

Researchers from Harvard University have successfully inserted genes from a woolly mammoth into living cells from an Asian elephant, the extinct giant's closest remaining relative. Harvard geneticist George Church used DNA from Arctic permafrost woolly mammoth samples to copy 14 mammoth genes -- emphasizing those related to its chilly lifestyle. "We prioritized genes associated with cold resistance including hairiness, ear size, subcutaneous fat and, especially, hemoglobin," Church told The Sunday Times. Then, using a kind of DNA cut/paste system called CRISPR (clustered regularly interspaced short palindromic repeat), Church dropped the genes into Asian elephant skin cells.
The result? A petri dish of elephant cells functioning normally with mammoth DNA in them, marking the first time mammoth genes have been on the job since the creature went extinct some 4,000 years ago, as Sarah Fecht, from Popular Science, noted...more